Overview

In May of 2013, the March of Dimes joined with Ohio’s leading universities and hospitals to launch the second prematurity research center aimed exclusively at finding the unknown causes of preterm birth. This video announcing the March of Dimes Prematurity Research Center Ohio Collaborative demonstrates the commitment and enthusiasm of accomplished directors, investigators and faculty as they come together in this transdisciplinary and cross-institutional effort to solve the mysteries of preterm birth.

The Ohio Collaborative research team includes over 100 faculty-level investigators, trainees, and staff and is led by its program directors, Louis J. Muglia, M.D., Ph.D., Irina A. Buhimschi, M.D. and Sam Mesiano, Ph.D. Five key research themes are being pursued via transdisciplinary interactions that will generate new research hypotheses and techniques to prevent preterm birth.

Watch the video (2:31 min.) >

 

Program Directors

Louis J. Muglia, M.D., PH.D. (Coordinating Principal Investigator and Program Director) is a Professor of Pediatrics at the University of Cincinnati and Vice Chair for Research, Co-Director of the Perinatal Institute and Director, Center for Prevention of Preterm Birth at Cincinnati Children’s Hospital Medical Center. As Coordinating Principal Investigator and Program Director of the March of Dimes Prematurity Research Center Ohio Collaborative, he works closely with the other program directors to lead the Collaborative’s effort to understand preterm birth. He also leads the Molecular Developmental Biology of Pregnancy research theme. For the last 25 years, Dr. Muglia has been at the forefront of research, professional education, science and clinical care in pediatrics. His expertise in genetics and endocrine signaling pathways has led to an innovative comparative genomic approach to identifying novel genes likely to be involved in the timing of birth. Dr. Muglia has mentored numerous graduate and postdoctoral students and trainees and has published more than 200 articles in leading peer-reviewed journals. He has been recognized with numerous awards, including a Burroughs Wellcome Fund Career Development Award, the Society for Pediatric Research Young Investigator Award and is a fellow at the American Association for the Advancement of Science. He is an elected member of the Institute of Medicine (IOM) of the National Academies and the American Society for Clinical Investigation.

Irina A. Buhimschi, M.D. (Program Director) is a Professor of Pediatrics and Obstetrics/Gynecology at The Ohio State University and the Director of the Center for Perinatal Research at the Research Institute of Nationwide Children’s Hospital. As Program Director, she has oversight responsibility for the Collaborative’s research efforts in the Columbus area and is also the leader of the Sociobiology of Racial Disparities in Preterm Birth research team. Dr. Buhimschi’s research interests span the broad area of understanding the molecular and pathophysiologic mechanisms of preterm labor and preeclampsia that together account for the large majority of preterm births. Her work has been supported by the NIH, March of Dimes, Bill & Melinda Gates Foundation, USAID and other funding agencies. She has more than 150 peer-reviewed publications, has served on numerous editorial boards and grant review committees and is a highly sought mentor for undergraduate students, clinical fellows and junior faculty.

Sam Mesiano, Ph.D. (Program Director) is a Professor of Reproductive Biology at Case Western Reserve University and Co-Director of the Research Division in the Department of Obstetrics and Gynecology at the University Hospitals of Cleveland. As Program Director and theme co-leader of Progesterone Signaling in Pregnancy Maintenance and Preterm Birth, he is a key member of the leadership team and directs the Case Western Reserve University, University Hospitals, and MetroHealth component of the collaborative. Dr. Mesiano’s expertise in understanding how progesterone promotes pregnancy and how its withdrawal is mediated to initiate labor in women will be critical for the long-term goal of developing therapeutics to prevent preterm birth by exploiting the natural pro-gestational actions of progesterone. He received the President’s Achievement Award from the Society for Gynecologic Investigation and is a member of the Preterm Birth International Collaborative, the Perinatal Research Society and the Global Alliance to Prevent Prematurity and Stillbirth.

Ohio Collaborative Co-Directors & Administrators

Sudhansu K. Dey, Ph.D. Professor of Pediatrics, Director of the Division of Reproductive Sciences, Cincinnati Children's Hospital Medical Center
James M. Greenberg, M.D. Professor of Pediatrics, Co-Director of the Perinatal Institute and Director of the Division of Neonatology, Cincinnati Children's Hospital Medical Center
Jay D. Iams, M.D. Zuspan Endowed Chair and Professor of Obstetrics and Gynecology, The Ohio State University
Mark A. Klebanoff, M.D., M.P.H. Professor of Pediatrics and Obstetrics/Gynecology, The Ohio State University and Director of the Ohio Perinatal Research Network, Principal Investigator in the Center for Perinatal Research, The Research Institute at Nationwide Children's Hospital
Brian M. Mercer, M.D. Professor of Reproductive Biology, Case Western Reserve University and Chair, Department of Obstetrics and Gynecology, MetroHealth Medical Center
Raymond W. Redline, M.D.
Professor of Pathology and Reproductive Biology, Case Western Reserve University
Jeffery A. Whitsett, M.D. Professor of Pediatrics, Co-Director of the Perinatal Institute, Director of Pulmonary Biology, and Chief of the Section of Neonatology, Perinatal, and Pulmonary Biology, Cincinnati Children's Hospital Medical Center
Joanne Chappell Director of Operations, MOD Prematurity Research Center Ohio Collaborative, Cincinnati Children's Hospital Medical Center

Ohio Collaborative Investigators

Patrick Abbot, Ph.D. Associate Professor of Biological Sciences, Vanderbilt University
William Ackerman, M.D. Assistant Professor and Co-Director, Laboratory of Perinatal Research, The Ohio State University
Michael Bailey, Ph.D. Associate Professor of Biosciences, The Ohio State University and Principal Investigator, Center for Microbial Pathogenesis, The Research Institute at Nationwide Children’s Hospital
Danielle Bessett, Ph.D. Assistant Professor of Psychology, University of Cincinnati
Thomas Brown, Ph.D. Professor and Vice Chair for Research, Department of Neuroscience, Cell Biology and Physiology, Wright State University
Catalin Buhimschi, M.D. Professor, Director of Maternal Fetal Medicine and Vice Chair for Research in the Department of Obstetrics and Gynecology, The Ohio State University
Irina Buhimschi, M.D. Professor of Pediatrics and Obstetrics/Gynecology, The Ohio State University and Director, Center for Perinatal Research, The Research Institute at Nationwide Children’s Hospital
Kenneth Campbell, Ph.D. Professor, Division of Developmental Biology, Cincinnati Children's Hospital Medical Center
John Anthony Capra, Ph.D. Assistant Professor, Vanderbilt University
Patrick Catalano, M.D. Professor of Reproductive Biology, Case Western Reserve University and past Chair of Obstetrics & Gynecology, MetroHealth Medical Center
Mark Chance, Ph.D. Vice Dean for Research, Professor of General Medical Sciences, Director of the Center for Proteomics and Bioinformatics, Case Western Reserve University
Lisa Christian, Ph.D. Assistant Professor of Psychiatry, Department of Psychiatry and The Institute of Behavioral Medicine Research, The Ohio State University
Sanjoy Das, Ph.D. Professor, Division of Reproductive Sciences, Cincinnati Children's Hospital Medical Center
Emily DeFranco, D.O., M.S.C.R. Associate Professor of Obstetrics & Gynecology, University of Cincinnati
Sudhansu K Dey, Ph.D. Professor of Pediatrics, Director of the Division of Reproductive Sciences, Cincinnati Children's Hospital Medical Center
David Greenberg, Ph.D. Professor of Pediatrics, The Ohio State University and Director of Neurogenetics, Nationwide Children’s Hospital
James Greenberg, M.D. Professor of Pediatrics, Co-Director of the Perinatal Institute, Director of the Division of Neonatology, Cincinnati Children's Hospital Medical Center
Ken Greis, Ph.D. Professor of Cancer and Cell Biology, University of Cincinnati
Joshua Gross, Ph.D. Assistant Professor of Biological Sciences, University of Cincinnati
Tamar Gur, M.D., Ph.D. Assistant Professor of Psychiatry, Neuroscience and Obstetrics & Gynecology, The Ohio State University
Eric Hall, Ph.D. Assistant Professor, Divisions of Neonatology and Biomedical Informatics, Cincinnati Children's Hospital Medical Center
John Harley, M.D., Ph.D. Professor of Pediatrics, Director, Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center
Jay Iams, M.D. Zuspan Endowed Chair and Professor of Obstetrics and Gynecology, The Ohio State University
Farrah Jacquez, Ph.D. Associate Professor of Psychology, University of Cincinnati
Suhas Kallapur, M.D. Professor of Pediatrics, Cincinnati Children’s Hospital Medical Center
Beena Kamath-Rayne, M.D., M.P.H. Associate Professor of Pediatrics, Cincinnati Children's Hospital Medical Center
Ozlem Kayisli, Ph.D. Assistant Professor, Department of Obstetrics and Gynecology, Morsani College of Medicine, University of South Florida
Umit Kayisli, Ph.D. Associate Professor, Department of Obstetrics and Gynecology, Morsani College of Medicine, University of South Florida
Sarah Keim, M.A., M.S., Ph.D. Assistant Professor of Pediatrics, The Ohio State University and Principal Investigator, Center for Biobehavioral Health, The Research Institute at Nationwide Children’s Hospital
Elizabeth Kelly, M.D. Associate Professor and Vice Chair, Department of Obstetrics & Gynecology, Director of Women's Community Health, University of Cincinnati
Mark Klebanoff, M.D., M.P.H. Professor of Pediatrics and Obstetrics/Gynecology at The Ohio State University and Director of the Ohio Perinatal Research Network, Principal Investigator in the Center for Perinatal Research, The Research Institute at Nationwide Children's
Douglas Kniss, Ph.D. Professor of Obstetrics and Gynecology, Director, Laboratory of Perinatal Research, The Ohio State University
Mehmet Koyuturk, Ph.D. Associate Professor, Department of Electrical Engineering & Computer Science and the Center for Proteomics & Bioinformatics, Case Western Reserve University
Charles Lockwood, M.D., M.H.C.M. Senior Vice President, USF Health and Dean, Morsani College of Medicine, University of South Florida 
Jennifer Malat, Ph.D. Associate Dean and Professor of Sociology, Research Director, Kunz Center for Social Research, University of Cincinnati
Ramkumar Menon, PhD, Assistant Professor of Obstetrics and Gynecology, The University of Texas Medical Branch at Galveston
Brian Mercer, M.D. Professor of Reproductive Biology, Case Western Reserve University and Chair, Department of Obstetrics and Gynecology, MetroHealth Medical Center
Sam Mesiano, Ph.D. Professor of Reproductive Biology, Case Western Reserve University and Co-Director, Research Division, Department of  Obstetrics and Gynecology, University Hospitals of Cleveland
John Moore, M.D. Professor of Reproductive Biology, Case Western Reserve University and Chief of Neonatology, MetroHealth Medical Center
Louis Muglia, M.D., Ph.D. Professor of Pediatrics, Co-Director of the Perinatal Institute and Director, Center for Prevention of Preterm Birth, Cincinnati Children's Hospital Medical Center
Reena Oza-Frank, Ph.D. Assistant Professor, Ohio State University and Principal Investigator, Center for Perinatal Research, The Research Institute at Nationwide Children’s Hospital
Mihaela Pavlicev, Ph.D. Assistant Professor, Center for Prevention of Preterm Birth, Cincinnati Children's Hospital Medical Center
Kenneth Petren, Ph.D. Professor and Dean, McMicken College of Arts and Sciences
Raymond Redline, M.D. Professor of Pathology and Reproductive Biology, Case Western Reserve University
Patricia Reagan, Ph.D. Professor Emiritas and Research Scientist, Center for Human Resource Research, The Ohio State University
Antonis Rokas, Ph.D.
 Professor of Biological Sciences and Biomedical Informatics, Cornelius Vanderbilt Chair of Biological Sciences, Vanderbilt University
Kelli Ryckman, Ph.D. Associate Professor, Department of Epidemiology, University of Iowa
Frederick Schatz, Ph.D. Professor, Department of Obstetrics and Gynecology, Morsani College of Medicine, University of South Florida
Kent Schwirian, Ph.D. Professor Emeritus, Department of Sociology, The Ohio State University
Patricia Schwirian, Ph.D., R.N. 
Professor Emerita, College of Nursing, The Ohio State University
Xiaofei Sun, Ph.D. Assistant Professor of Pediatrics, Department of Reproductive Sciences, Cincinnati Children’s Hospital Medical Center
Sing Sing Way, M.D., Ph.D.
 
Professor and Pauline and Lawson Reed Chair, Division of Infectious Diseases, Cincinnati Children’s Hospital Medical Center
Jeffery Whitsett, M.D. Professor of Pediatrics, Co-Director of the Perinatal Institute, Director of Pulmonary Biology, and Chief of the Section of Neonatology, Perinatal, and Pulmonary Biology, Cincinnati Children's Hospital Medical Center
Scott Williams, Ph.D. Professor of Epidemiology and Biostatistics and Genetics and Genome Sciences, Case Western Reserve University
Honor Wolfe, M.D. Professor, Division Chief of Maternal Fetal Medicine, Case Western Reserve University
Ge Zhang, M.D., Ph.D. Associate Professor, Division of Human Genetics, Cincinnati Children's Hospital Medical Center

Ohio Collaborative Oversight Committee
(In Addition to Program Directors & Co-Directors)

John Barnard, M.D. President, The Research Institute at Nationwide Children’s Hospital and Professor and Vice-Chair for Research, Department of Pediatrics, The Ohio State University
Thomas Boat, M.D. Former Dean and Senior Vice President for Health Affairs, University of Cincinnati College of Medicine.
Mark Chance, Ph.D. Vice Dean for Research, Professor of General Medical Sciences, Director of the Center for Proteomics and Bioinformatics, Case Western Reserve University
Alfred Connors, Jr., M.D. Chief Medical Officer, MetroHealth and Senior Associate Dean and Professor of Medicine, Case Western Reserve University
Carlo Croce, M.D. Chair, Department of Molecular Virology, Immunology & Medical Genetics and Director, Institute of Genetics, The Ohio State University
Pamela Davis, M.D., Ph.D. Dean of Medicine and Professor of Pediatrics, Physiology & Biophysics, Case Western Reserve University
Arthur Evans III, M.D. Professor and Chairman of Obstetrics and Gynecology, University of Cincinnati College of Medicine
Michael Fisher, President and CEO, Cincinnati Children’s Hospital Medical Center
Steven Gabbe, M.D. CEO Emeritus and Professor, Obstetrics and Gynecology
James Heubi, M.D. Professor of Pediatrics, Director of the CCTST and General Clinical Research Center, Associate Dean for Clinical and Translational Research, University of Cincinnati
Margaret Hostetter, M.D. Chair and Professor of Pediatrics, University of Cincinnati, Director, Cincinnati Children’s Research Foundation, Chief Medical Officer, Cincinnati Children’s Hospital Medical Center
Uma Kotagal, M.B.B.S., M.S.C. Senior Vice President for Quality and Transformation and Director of Health Policy and Clinical Effectiveness, Cincinnati Children’s Hospital Medical Center
Mark Landon, M.D. Chair and Professor, Department of Obstetrics and Gynecology, The Ohio State University Wexner Medical Center
James Liu, M.D. Arthur H. Bill Professor and Chair of Reproductive Biology, Case Western Reserve University
Arnold Strauss, M.D. Professor of Pediatrics and Associate Director, Cincinnati Children’s Research Foundation, Cincinnati Children’s Hospital Medical Center